SEEK: Salford Environment for Expertise and Knowledge
Dr Chloe James
Dr Chloe James
postal addressPeel Building (Room G28), The Cresent, Salford, Greater Manchester, UK, M5 4WT.
telephone0161 295 2171
website address
Key Memberships
Full Member of Research Centre: Biomedical Research Centre
From September 2015 to present.
Associate Member of Research Centre: Ecosystems and Environment Research Centre
From January 2015 to present.
From January 2013 to August 2015.
Profile Summary

 My chief research interests lie in bacterial pathogenicity, development and spread of antibiotic resistance and in how microbial evolution is driven by interaction with microbial communities and their environments. I am particularly interested in Gram negative bacteria in multi-species biofilms and bacteriophages. I have worked in the UK, USA and France on molecular aspects of pathogenicity, regulation and antibiotic resistance in Escherichia coli, Porphyromonas gingivalis, Streptococcus gordonii; Enterobacter aerogenes; Pseudomonas aeruginosa; Campylobacter jejuni.

Key Qualifications
Shigatoxigenic E. coli (STEC) are dangerous foodborne pathogens, defined by their production of potent shiga toxins (stx), which are encoded on a group of temperate stx bacteriophages. My PhD investigated the capacity of shiga toxin-encoding phages from E. coli O157 for horizontal gene transfer. I determined the host range of shiga toxin-encoding phage (Φ24B) from E. coli O157 and modelled its survival in soil microcosms. My work lead to the identification of a bacterial receptor for Φstx infection.
Key Projects
MicroBiHome (MSF 2018)
The Physiological Society, £5,000.00.
Principal Investigator: S Withers (50%). Co-Investigator: C James (50%).
Key Publications
Refereed Journal Articles
Book Sections