I started my research training as an undergraduate student in Italy at the University of Rome “La Sapienza” , where I worked as volunteer for two years in Dr. Bozzoni laboratory learning about RNA and its multiple functions and extraordinary plasticity.
I graduated cum laude in 2004 and with the support of the Italia-USA Program Fellowship, I moved to USA to join Dr. Croce laboratory where I completed in 2009 my PhD, based both at University of Ferrara and Ohio State University.
In Dr. Carlo M. Croce’s laboratory, I had the opportunity to see how simple biomolecular ideas and experimental approaches can acquire a therapeutic dimension and a bedside perspective. During this time, I acquired an interest in the role of small non-coding RNAs and their involvement in cancer by showing how they reprogramme gene expression to confer proliferative advantage to cancer cells and induce resistance to therapeutic agents.
In 2014, I decided to move with my family to Manchester where I joined Dr. Richard Marais group at CRUK-Manchester Institute and had the opportunity to work in drug discovery for the development of new drugs targeting cancer stem cells. Last December, I started my position at Salford as Lecturer in Biomedical Sciences. I will focus on my long-standing interest in exploring the molecular roles of non-coding RNAs in determining cell fate changes and gene regulation. I really believe that discovering how non-coding RNAs regulate gene expression will improve our understanding of development and disease and it will allow the development of novel therapeutic strategies.