SEEK: Salford Environment for Expertise and Knowledge
Dr Pika Miklavc
Dr Pika Miklavc
Key Memberships
From October 2016 to present.
Profile Summary

My research focuses on secretory processes in lung epithelial cells. The lungs contain several secretory cell types which use regulated exocytosis. Secretory cells in the airways release mucins, which help to keep the lungs free of pathogens. In contrast, secretory type II cells of the lung alveoli secrete lipo-protein surfactant, which reduces surface tension of the alveolar lining fluid and enables inspiration. Alveolar type II cells have large secretory vesicles and a particularly slow, sequential fusion process, which makes them an ideal cell model to study single vesicle fusion events in living cells by using high-resolution microscopy methods. My research encompasses different stages of exocytosis, with focus on regulation of vesicle content release after fusion pore opening.

In addition to investigating basic mechanisms of secretion I am interested in pathological alterations of the secretory mechanisms in lung cells and their implications for lung function.

Key Qualifications
2005
2015
Key Projects
2018
Oct
KidsCan Placement Student Grant Scheme-Bench Fees
Kidscan, £2,000.00.
Principal Investigator: P Miklavc (100%).
Key Publications
Refereed Journal Articles
Other Journal Articles
Thesis
Key Presence
Conference Presentations
2016
Jun
2016
Mar
2015
Aug
2015
Mar
2014
Dec
2014
Dec
2014
Jun
2014
Mar
2014
Mar
2013
Mar
2011
Mar
2010
Jul
2009
Nov
2009
Sep
2005
Apr
2004
Jun
Invited Papers and Lectures
2016
Mar
2008
Mar