Journal Article (Refereed)
The role of the hypothalamus part 2: Regulation of sleep┐ wake cycles and effect on pain
Braine, M 2009, 'The role of the hypothalamus part 2: Regulation of sleep┐ wake cycles and effect on pain', British Journal of Neuroscience Nursing , 5(3), pp.113-120.
The hypothalamus forms part of the so-called central autonomic network, regulating body homeostasis, sleep and controlling pain. Although several parts of the brain have been implicated in the complex mechanism of sleep, this paper will explore the key hypothalamic regions in the regulation of sleep: its anterior region is implicated in sleep facilitation, while the posterior hypothalamus region acts in a balanced way to maintain wakefulness. To simplify this sleep-wake cycle, key individual areas involved are firstly described. Disruption of the sleep-wake cycle can result in a wide range of diseases and disorders, causes of a few of these are discussed, along with their symptoms, including seasonal affective disorder, cancer, Parkinson’s disease, narcolepsy and other neurological conditions. Finally the influence on the perception of pain is presented along with the role the hypothalamus plays in pain disorders such as cluster headaches and migraine
British Journal of Neuroscience Nursing